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Dermatology Glossary


Leukemia cutis

In patients with leukemia, infiltrates of the skin are not uncommon. Infiltrations of the skin are most commonly produced by monocytic or myelomonocytic leukemia, which can produce a diffuse infiltration of the face (leonine facies).
The infiltrated skin usually has a purple hue.
Involvement of the skin can be a presenting feature in the myelomonocytic leukemia, although generally it occurs late in the course of the disease.

Treatment:

  • Treatment of the systemic leukemia usually results in clearing of the skin lesions.
  • Lesions also respond well to local radiotherapy.
leukemia cutis

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